⚠️ For licensed healthcare professionals only. Physician verification required.
🏥 Doctor Opus

📘 Physician Manual

📘 Doctor Opus — Physician User Guide

Important: Doctor Opus is a Clinical Decision Support System (CDSS) for licensed healthcare professionals only. It is not FDA-approved and does not constitute a medical diagnosis. All AI-generated outputs require independent clinical verification. You bear full responsibility for all clinical decisions.

Doctor Opus accelerates your clinical workflow by providing AI-assisted interpretation of medical imaging, lab data, genetic reports, and clinical notes. Each section contains contextual tips — review them on first use.

The application runs on desktop and mobile. Both can work independently or in tandem via the cross-device sync module.

📱 Install as a Mobile App (PWA)

The platform is a Progressive Web App — install it on your home screen for native-like access.

iPhone (Safari)

  1. Open doctor-opus.online in Safari
  2. Tap the Share button (square with arrow) at the bottom
  3. Scroll down and select "Add to Home Screen"
  4. Tap "Add" in the top-right corner
  5. Done — the Doctor Opus icon will appear on your home screen

Android (Chrome)

  1. Open doctor-opus.online in Chrome
  2. Tap the three-dot menu (⋮) in the top-right corner
  3. Select "Add to Home Screen" or "Install App"
  4. Confirm installation
  5. Done — the icon will appear on your home screen

Once installed, the app opens full-screen, is accessible via icon, and works even with a poor connection (except AI features that require the network).

🏠 Home

Overview dashboard with quick navigation to all sections.

🤖 AI Assistant

The core intelligence of the platform. Supports open-ended clinical dialogue, case discussion, differential diagnosis, literature review, and multi-file analysis.

Available models (dropdown):

  • GPT-5.2 — Best for 80% of imaging, MRI, and general clinical questions. Concise and efficient.
  • Claude Opus 4.6 — Deepest reasoning. Best for complex cases, genetics, and rare pathologies. Slower, higher cost.
  • Claude Sonnet 4.6 — Balanced. Excellent for quick consultations and fracture assessment.
  • Gemini 3.1 Flash — Fastest. Ideal for quick reference and data extraction.

The assistant can:

  • Answer clinical questions and sustain multi-turn dialogue
  • Accept results exported from any other section
  • Specialize as a consultant (Cardiologist, Neurologist, Orthopedist, etc.)
  • Perform literature review and evidence-based searches
  • Process uploaded files (images, PDFs, Word documents)
  • Use your Personal Library (RAG) — when enabled, the assistant draws answers from your own uploaded PDF guidelines and references

PHI reminder: Do not enter patient names, dates of birth, or other identifying information in the chat. Use anonymized descriptions (e.g., "65 y.o. male, smoker, 3-week cough").

📚 Personal Library (RAG)

Upload your own PDF clinical guidelines, textbooks, and atlases. Once processed, the AI Assistant can search them and cite relevant excerpts directly in the analysis output.

  • Capacity: up to ~1 GB (larger collections may slow the browser on low-end hardware)
  • Files are processed on your local server — not sent to external services
  • Use text-searchable PDFs (not scans) for best results

📝 Clinical Protocol (Voice-to-Note)

Converts unstructured dictation or typed notes into a structured, specialty-specific clinical note — ready to download as a Word (.docx) file, edit, and sign.

How to use

  1. Select your specialty from the dropdown (Cardiology, Neurology, Orthopedics, etc.)
  2. Dictate or type the encounter notes in any order — the AI structures them automatically
  3. Click Generate Protocol — the formatted note appears in the right panel
  4. Download as .docx, review, and sign

Note structure follows SOAP / H&P format:

  • S — Subjective (CC, HPI, PMH, medications, allergies)
  • O — Objective (vitals, PE findings)
  • A — Assessment (working diagnosis, differential)
  • P — Plan (diagnostics, treatment, follow-up)

You can customize any template to match your workflow. The customized version can be pinned as your personal standard.

Recommended models: GPT-5.2 or Claude Sonnet 4.6.

🧮 Medical Calculators

Launches an integrated third-party calculator suite. Runs client-side — no credits consumed, no data transmitted.

📋 Clinical Guidelines

Search current international clinical guidelines by condition, syndrome, or drug class.

Search depth options:

  • Standard — concise protocol summary with key recommendations
  • Clinical Review — deep analysis: differential, scoring scales (CHADS₂, Wells, CURB-65, etc.), step-by-step management, treatment algorithms
  • Real-time Search — latest 2024–2025 publications with source links

After receiving results, you can continue the conversation with follow-up questions in context.

🔬 Specialized Analysis Modules

📈 ECG Analysis

Workflow:

  1. Upload an ECG image (JPG, PNG, or PDF scan)
  2. Add clinical context (CC, HPI, relevant medications) — significantly improves accuracy
  3. Use the 🛡️ anonymization buttons before submitting:
    • Quick: Auto-redacts edges and corners
    • Precision: Brush editor for exact redaction
  4. Select analysis mode (Fast / Optimized / Expert Validated)

Additional tools:

  • Digital Caliper: Drag blue markers to measure PR, QRS, QT intervals. Calibrate using the ECG grid (1 sec = 5 large cells at 25 mm/s)
  • Search Library: After analysis, click to find matching cases or descriptions in your personal PDF library

Recommended models: GPT-5.2 (general) · Claude Sonnet 4.6 (arrhythmia detail)

🩻 X-Ray Analysis

Upload single or multiple images (folder or DICOM series). Add clinical context for significantly better output.

Anonymization:

  • Quick: auto-redacts standard PHI zones
  • Precision: manual brush editor
  • DICOM: metadata stripped automatically

Comparison mode: Enable Before/After to compare two time points or views side-by-side.

Best models: GPT-5.2 (80% of cases) · Claude Sonnet 4.6 (fractures, 83% accuracy)

🧠 CT Analysis

Upload CT images or an entire DICOM folder.

3D Viewer (DICOM series):

  • MPR 2×2: Axial / Coronal / Sagittal slices + volumetric model
  • Cinematic 3D ✨: Full-screen photorealistic rendering with soft shadows
  • Clinical presets: Bone, Soft tissue (X-ray effect), Glow (highlights pathological foci)
  • Scroll slices with mouse wheel · Zoom · Free 3D rotation
  • M1 chip: hardware-accelerated rendering

PHI anonymization: manual and automatic (DICOM metadata auto-stripped).

🧠 MRI Analysis

Identical workflow to CT. Supports multi-sequence DICOM series with full MPR and Cinematic 3D rendering.

🔊 Ultrasound Analysis (Cine-loop)

Upload a static image or a video loop (cine-loop).

Frame extraction:

  • Auto-Extract: System automatically extracts 5–12 key frames
  • Manual Capture: Step through with ±0.1s buttons and capture the exact frame

All frames are anonymized before submission (black bars on edges).

🔬 Dermatoscopy Analysis

Upload dermatoscopy images. Add clinical context (lesion location, duration, observed changes). Supports ABCDE criteria analysis and malignancy risk assessment.

🧪 Laboratory Data Analysis

Upload a lab report (PDF, Excel, CSV, or photo of a paper form).

Smart extraction: System automatically recognizes parameters, values, and reference ranges — even from multi-page PDFs or handwritten forms.

Analysis output includes:

  • Critical value flagging
  • Clinical interpretation in the context of provided HPI
  • Trend graphs (if patient is in your database)

🧬 Genetic Analysis

Upload a genetic report in .VCF format (raw lab output) or PDF.

Workflow:

  1. Upload file
  2. Stage 1 (Extract): Gemini 3.1 Flash extracts rsIDs and genotypes from the report
  3. Stage 2 (Interpret): Claude Opus 4.6 provides clinical risk interpretation
  4. Continue dialogue with the Genetics specialist for follow-up questions

Always anonymize before submitting (name and address auto-redacted on the preview screen).

🎬 Video Clinical Analysis

Upload any video file (patient gait, endoscopy, echocardiography, ultrasound loop, etc.).

Two modes:

| Mode | Description | Use when | |---|---|---| | Safe (frame extraction) | System extracts 5–12 frames, anonymizes each, shows preview | Default — any video with or without PHI | | Full video | Entire file sent unprocessed | Only for already-anonymized files |

⚠️ In Full Video mode, frames are NOT anonymized automatically. Confirm absence of PHI before using.

🔍 Comparative Analysis

Side-by-side comparison of medical images across time or location.

Comparison modes:

  • Over Time — progression assessment (before/after treatment)
  • By Location — comparing scans of different anatomical regions
  • General — free-form multi-image comparison

Supports both single images and video/DICOM folder batches.

🔬 Advanced Analysis (Image + Context)

Upload a primary image plus optional additional files (PDFs, Word documents, photos). Add detailed clinical context. Receive a unified clinical directive combining all inputs.

🧊 Advanced 3D Visualization (Cinematic)

Dedicated high-fidelity volumetric rendering for MRI and CT DICOM series.

  • Cinematic Mode: Volume scattering for photorealistic organ rendering
  • Vessel Highlight: Vessels and contrast-enhanced areas shown in red; surrounding tissue becomes semi-transparent
  • Adaptive quality: Lower resolution while rotating for smooth performance; restores to HQ at rest
  • Apple M1 optimization: Automatic downsampling for heavy studies to maintain frame rate

📄 Document Scanning

Turns your smartphone camera into a document scanner.

Local Copier (browser mode)

Works entirely in your browser — no AI, no internet required. 100% private.

Features:

  • Brightness, contrast, and grayscale adjustments
  • Export to Word (.docx) or PDF (via system print dialog)
  • Free — no credits consumed

Smart OCR (AI mode)

Extracts text and tables from scanned documents for further processing.

PHI protection:

  • Mandatory anonymization toggle
  • Auto-redaction of names and addresses when enabled
  • 🎨 Manual Redact editor: paint over any sensitive area before submitting

👥 Patient Database

Local patient records stored in your browser's IndexedDB — data never leaves your device.

Features:

  • Add patients with name (anonymized alias recommended), age, gender, diagnosis, notes
  • Save analysis results to patient records from any analysis section
  • View analysis history, timeline, and lab value trend charts
  • AI case summary: one-click narrative summary of all saved analyses for a patient

🔌 Direct Device Connection (USB)

Read data from ECG monitors, pulse oximeters, glucometers, and other serial-interface devices directly through the browser — no drivers required.

  1. Go to the Devices section
  2. Select baud rate (usually 115200)
  3. Click Connect and select your device from the browser prompt (Chrome / Edge only)
  4. View live ECG curve or sensor data
  5. Click Analyze fragment for immediate AI interpretation of the current segment

🛡️ Privacy & Data Handling

Doctor Opus is built on a Local-First principle — patient data stays on your device.

| Data type | Storage location | Leaves the device? | |---|---|---| | Patient cards & analysis history | Browser IndexedDB | Never | | Medical images during analysis | Browser RAM | Only anonymized fragments | | AI results (saved) | Browser IndexedDB | No | | User account & credit balance | Cloud PostgreSQL | Yes (no medical data) | | Analysis statistics (anonymized) | Cloud PostgreSQL | Yes (no PHI) |

Three-level anonymization before any AI call:

  1. Browser-side text regex — names, dates, IDs stripped
  2. Image canvas redaction — PHI zones painted black
  3. Server-side recursive scrub — all request fields cleaned before OpenRouter

No Personal Health Information (PHI) or Personally Identifiable Information (PII) linked to medical scans is stored in the cloud database.

💰 Credit System

Credits are consumed when using advanced AI models. Simple reference lookups and local tools are free.

| Operation | Credit cost (approx.) | |---|---| | Fast analysis (Gemini 3.1 Flash) | ~0.3 – 0.8 cr. | | Optimized analysis (Sonnet 4.6) | ~0.8 – 1.5 cr. | | Expert Validated (Opus 4.6 / GPT-5.2) | ~1.5 – 3.5 cr. | | PDF page (Vision processing) | ~0.3 cr. per page | | Local copier / calculators | Free |

Packages:

  • Starter: 50 credits — $9.99
  • Standard: 150 credits — $24.99
  • Pro: 500 credits — $69.99

Exact cost of each request is shown in the result block immediately after analysis completes. Full transaction history is available in Balance & History.

💡 Tips for Best Results

  • Always add clinical context (CC, HPI, key PMH) — it significantly improves relevance and accuracy
  • Use text-searchable PDFs (not image scans) for the Personal Library
  • For ECG: use Claude Sonnet 4.6 in Optimized mode for arrhythmia detail
  • For fractures: Claude Sonnet 4.6 outperforms other models (83% accuracy)
  • For complex genetics or rare pathology: use Claude Opus 4.6 (Expert Validated mode)
  • The system improves over time through your feedback — please rate AI responses after tests